| Are
your genes are making you fat?
They
definitely could be. Scientists have discovered a commonly
occurring obesity gene called FTO that is found in
a large percent of the population. The FTO gene occurs in
over half the people of European descent, and scientists are
now studying the DNA of African Americans and Asians to determine
the percent of non-Europeans that have the FTO gene.
The
study included 40,000 human subjects, which is one of the
largest studies ever conduced on obesity. Results were conclusive;
the FTO variant causes weight gain, obesity, and type 2 diabetes
in humans.
The
FTO gene variant regulates the amount of fat in the body and
explains why some people are more overweight than others,
while eating the same foods.
The
impact of the gene depends on whether an individual has inherited
one or two copies of the FTO variant. Person who have two-copies
of the FTO gene are 70 percent more likely to be
obese than non-carriers of the gene. This equates to a hard-wired
internal fat-storing mechanism that piles on the
weight in persons carrying the gene.
Genetic
researchers note that human genetics have not changed in the
last 100 years, but lifestyle and environment have, and this
exacerbates fat-storage of foods and beverages.
The
World Health Organization (WHO) estimates that about
2 billion people worldwide are obese or overweight. This means
that 1/3 of all persons over the age of fifteen are either
overweight or obese.
These
statistics are alarming, and particularly for children, as
20 million kids under age 6 are obese or overweight. An overweight
child typically turns into an overweight or obese adult due
to Progenitor fat cells developed in childhood.
The
impact of the discovery of this gene is significant. Pharmaceutical
researchers are rushing to identify and patent new drugs that
will help control weight in persons with active FTO genes.
The
biological mechanism behind the FTO gene regulates weight
control and body fat. The FTO gene also plays a role in appetite-regulation.
DOES
YOUR DNA RULE YOUR DESTINY?
Two
main factors determine the actions of the FTO gene. One is
exercise and the other is what you eat and drink.
In
a study of more than 700 Amish people, the FTO gene had no
appreciable effect on their weight, because of their diet
and exercise regimens. Amish persons are extremely physically
active, which helps negate the effects of the FTO gene. They
walk instead of drive, and they do not eat the typical American
diet. Their diet consists of home-grown fruits and vegetables.
The Amish do not ingest soft drinks, fast-foods,
high glycemic foods and snacks.
In
order to address the weight gain and fat-storing effects of
the FTO gene, Nuvo
Gene Tea™
consulted with one of the world’s leading human geneticists,
Clair Francomano, M.D. from Johns Hopkins University. Dr.
Francomano concurred with our scientists on preventive measures
related to fat-stimulating genetic variants, and has authored
a paper on this topic:
The
Nuvo
Gene Tea™
formula addresses the underlying mechanisms related to weight
gain, obesity, and genetic variants that trigger the storage
and formation of belly fat (adipose tissue fat).
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